研究業績
原著論文（Original Articles）
＊Corresponding
2024
Miyaji T, Kasuya R, Sawada A, Sawamura D, Kitaoka Y, Miyazaki M*. Akt1 deficiency does not affect fiber type composition or mitochondrial protein expression in skeletal muscle of male mice. Physiological Reports. 2024 September;12:e70048. https://doi.org/10.14814/phy2.70048
2023
Miyazaki M*, Sawada S, Sawamura D and Yoshida S. Decreased insulin-like growth factor-1 expression in response to mechanical loading is associated with skeletal muscle anabolic resistance in cancer cachexia. Growth Hormone & IGF Research. 2023;69-70: 101536. https://doi.org/10.1016/j.ghir.2023.101536
2022
Miyazaki M*, Shimozuru M, Kitaoka Y, Takahashi K and Tsubota T. Regulation of protein and oxidative energy metabolism are down-regulated in the skeletal muscles of Asiatic black bears during hibernation. Scientific Reports. 2022;12: 19723. https://doi.org/10.1038/s41598-022-24251-0
Sawamura D, Tanabe Y, Sakuraba S, Cui J, Miura H, Saito R, Sugi M, Watanabe A, Tokikuni Y, Sugawara K, Miyazaki M, Miyamoto R, and Sakai S. The impact of visual cross-modal conflict with semantic and nonsemantic distractors on working memory task. A functional near-infrared spectroscopy study. Medicine. 2022;101(36): e30330.
Miyazaki M*, Shimozuru M and Tsubota T. Supplementing cultured human myotubes with hibernating bear serum results in increased protein content by modulating Akt/FOXO3a signaling. PLOS ONE.2022;17(1): e0263085.
2021
Kitaoka Y, Miyazaki M* and Kikuchi S. Voluntary exercise prevents abnormal muscle mitochondrial morphology in cancer cachexia mice. Physiological Reports. 2021 August;9(16):e15016.
Nishida K, Shimozuru M, Okamatsu‐Ogura Y, Miyazaki M, Soma T, Sashika M and Tsubota T. Changes in liver microRNA expression and their possible regulatory role in energy metabolism‐related genes in hibernating black bears. Journal of Comparative Physiology B. 2021;191:397–409.
Klinosky DJ, Miyazaki M, et al. (著者多数), Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Jan;17(1):1-382.
2020
Miyazaki M*, Moriya N and Takemasa T. Transient activation of mTORC1 signaling in skeletal muscle is independent of Akt1 regulation. Physiological Reports. 2020 Oct;8(19):e14599.
Sugi M, Sakuraba S, Saito H, Miyazaki M, Yoshida S, Kamada T, Sakai S and Sawamura D. Personality Traits Modulate the Impact of Emotional Stimuli During a Working Memory Task: A Near-Infrared Spectroscopy Study. Front. Behav. Neurosci. 2020;14:514414.
2019
Miyazaki M*, Shimozuru M and Tsubota T. Skeletal muscles of hibernating black bears show minimal atrophy and phenotype shifting despite prolonged physical inactivity and starvation. PLOS ONE.2019;14(4):e0215489.
Kakuta D, Seto S, Kiso R and Miyazaki M*, Voluntary Wheel Running Prevents Skeletal Muscle Atrophy by Modulating Ubiquitin-proteasome-dependent Proteolysis in Cancer Cachexia Mice. Physical Therapy Japan.2019;46(2):73-82. (written in Japanese, English abstract available)
2018
Tatebayashi D, Himori K, Yamada R, Ashida Y, Miyazaki M and Yamada T. High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice. PLOS ONE. 2018;13(6):e0199050.
Moriya N and Miyazaki M*, Akt1 deficiency diminishes skeletal muscle hypertrophy by reducing satellite cell proliferation, American Journal of Physiology -Regulatory, Integrative and Comparative Physiology-, 2018;314(5):R741-R751.
2017以前
Miyazaki M* and Takemasa T, TSC2/Rheb signaling mediates ERK-dependent regulation of mTORC1 activity in C2C12, FEBS Open Bio, 2017 Mar;7(3):424-33.
Miyazaki M, Schroder E, Edelmann S, Balke CW, and Esser KA, Age-Associated Disruption of Molecular Clock Expression in Skeletal Muscle of the Spontaneously Hypertensive Rat, PLoS ONE, 2011, 2011;6(11):e27168.
McCarthy JJ, Mula J, Miyazaki M, Erfani R, Garrison K, Farooqui AB, Srikuea R, Lawson BA, Grimes B, Keller C, Van Zant G, Campbell KS, Esser KA, Dupont-Versteegden EE and Peterson CA, Effective fiber hypertrophy in satellite cell-depleted skeletal muscle, Development, 2011 Sep;138(17):3657-66.
Miyazaki M, McCarthy JJ, Fedele MJ and Esser KA, Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling, The Journal of Physiology, 2011 Apr;1(589 Pt 7):1831-46. Selected as Editor’s Choice and Perspective.
Miyazaki M, McCarthy JJ and Esser KA, IGF-1-induced phosphorylation and altered distribution of TSC1/TSC2 in C2C12 myotubes, the FEBS Journal, 2010 May;277(9):2180-91.
Miyazaki M and Esser KA, REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch, American Journal of Physiology -Cell Physiology-, 2009 Mar;296(3):C583-92.
Drummond MJ, Miyazaki M, Dreyer HC, Pennings B, Dhanani S, Volpi E, Esser KA, and Rasmussen BB, Expression of growth-related genes in young and old human skeletal muscle following an acute stimulation of protein synthesis, Journal of Applied Physiology, 2009 Apr;106(4):1403-11.
Miyazaki M, Noguchi M and Takemasa T, Intermittent reloading attenuates muscle atrophy through modulating Akt/mTOR pathway, Medicine and Science in Sports and Exercise, 2008, 40 (5), 848-855.
Miyazaki M, Hitomi Y, Kizaki T, Ohno H, Katsumura T, Haga S and Takemasa T, Calcineurin mediated slow-type fiber expression and growth in reloading condition, Medicine and Science in Sports and Exercise, 2006, 38 (6), 1065 -1072.
Miyazaki M, Hitomi Y, Kizaki T, Ohno H, Haga S and Takemasa T, Effects of intensity and duration of endurance exercise on skeletal muscle fiber type transition in mice, Advances in Exercise and Sports Physiology, 2005, 11 (1), 15-20
Miyazaki M, Hitomi Y, Kizaki T, Ohno H, Haga S and Takemasa T, Contribution of the calcineurin signaling pathway to overload-induced skeletal muscle fiber-type transition, Journal of Physiology and Pharmacology, 2004, 55 (4), 751-764
Takemasa T, Sugimoto K, Miyazaki M, Machida M, Ikeda S, Hitomi Y, Kizaki T, Ohno H, Yamashita K and Haga S, Simple method for the identification of oxidative fibers in skeletal muscle, European Journal of Applied Physiology, 2004, 91 (2-3), 357-359
総説（Reviews）
Miyazaki M, Growth factor-dependent and independent regulation of skeletal muscle mass -Is IGF-1 necessary for skeletal muscle hypertrophy?-, Journal of Physical Fitness and Sports Medicine, 2013 Jan;2(1):1-6.
Miyazaki M, Molecular Mechanisms regulating Skeletal Muscle Hypertrophy, Journal of Health, Physical Education and Recreation, 2010 Oct;60(10):713-718.
Esser KA, McCarthy JJ and Miyazak M, IGF-1 is not key for adult skeletal muscle hypertrophy, Letters to Point: Counterpoint “IGF is / is not the major physiological regulator of muscle mass.”, Journal of Applied Physiology, 2010 Jun;108(6):1830.
Miyazak M, The circadian clock and skeletal muscle function, Japanese Journal of Physical Fitness and Sports Medicine, 2010 Jun;59(2):233-42.
Miyazak M and Esser KA, Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals, Journal of Applied Physiology, 2009 Apr;106(4):1367-73.
書籍（Books & Chapters）
Miyazaki M, Physical Exercise and Skeletal Muscle Adaptation in Cancer Cachexia, Physical Therapy and Research in Patients with Cancer, Editors: Shinichiro Morishita, Junichiro Inoue, Jiro Nakano, SPRINGER NATURE, Switzerland, 2022, Pages 253-274, ISBN: 978-981-19-6710-8
Miyazaki M, Cellular mechanisms regulating protein metabolism in skeletal muscle cell -Age-associated alteration of intracellular signaling governing protein synthesis and degradation-, Basic Biology and Current Understanding of Skeletal Muscle, Editor: Kunihiro Sakuma, Nova Biomedical, New York, USA, 2013, 21-52, ISBN: 978-1-62808-367-5
Miyazaki M, Molecular mechanisms regulating protein synthesis and skeletal muscle hypertrophy through mTOR signaling, Current Research Trends on Skeletal Muscle, Editor: Kunihiro Sakuma, Research Signpost, India, 2012, 19-40
